PharmaBlock Sciences (Nanjing) , Inc.

PharmaBlock Sciences (Nanjing), Inc. is a prominent provider of innovative chemistry products and services that support the pharmaceutical research and development process as well as commercial production. Established in 2008 and listed on the Shenzhen Stock Exchange in 2017, the company specializes in the design, synthesis, and supply of novel building blocks, which are essential for accelerating drug discovery and development. PharmaBlock collaborates with leading pharmaceutical companies and numerous biotech firms globally to enhance their R&D capabilities through advanced chemistry and low-carbon technologies. The company's core business lines include the development of novel building blocks, building blocks-driven libraries for drug discovery, and fully integrated contract development and manufacturing organization (CDMO) services. PharmaBlock's drug discovery platform leverages its extensive collection of building blocks and includes tools such as Fragment-based Library for Drug Design and DNA-encoded Library Technology. Additionally, PharmaBlock focuses on sustainable manufacturing processes through advanced technologies like flow chemistry and biocatalysis, ensuring reliable supply and compliance with quality standards in drug development and commercial production.

1、Novel Building Blocks Since its establishment, PharmaBlock has rapidly gained recognition for its outstanding capabilities in the design, synthesis, and supply of novel building blocks. The team has generated a large and unique collection of high-quality and diverse building blocks, which are increasingly adopted by drug hunters to enrich the structure options, improve compound quality, expand patent space and eventually accelerate drug discovery projects. PharmaBlock has also been strengthening process R&D capabilities and expanding manufacturing capacity to secure the sustainable supply of building blocks. Based on the accumulation of building blocks, and chemistry know-hows, PharmaBlock extends its business scope and delivers its commitment to more comprehensive and long-term service to valued customers. 2、Building Blocks Driven Libraries for Drug Discovery Inspired by the large and unique collection of building blocks, PharmaBlock has established a powerful drug discovery platform for medicinal chemists to identify leads quickly. This platform includes a set of efficient tools, including but not limited to Fragment-based Library for Drug Design (FBDD), DNA-encoded Library Technology (DELT), and Virtual Screening. 3、Fully Integrated CDMO for Drug Development & Commercial Led by an experienced management and core technical team, PharmaBlock is providing development and manufacturing solutions of intermediates, drug substances, and drug products for development and commercial stages. Taking full advantage of building blocks availabilities, along with its know-hows in chemistry, process development, analytical development, GMP manufacturing, and engineering technologies, etc., the team has distinguished itself for capabilities to deliver integrated CMC services, tackle challenging chemistry, secure reliable supply, control cost with full compliance of quality and EHS, etc. 4、Low-carbon Technologies To further realize safe, efficient and green process development and manufacturing, PharmaBlock has developed an advanced chemistry and engineering technology platform, featuring flow chemistry, micropacked bed hydrogenation, biocatalysis, heterogeneous catalysis, crystallization, solid-state chemistry, etc. The technology platform has enabled more innovative solutions, with shortened lead time and reduced overall costs for development and manufacturing projects.